طراحی یک حسگر زیستی جدید ضریب شکستی مبتنی بر بلورفوتونی مناسب جهت تشخیص دی‌ان‌ای

نوع مقاله : فوتونیک

نویسندگان

1 گروه فوتونیک، دانشگاه جامع امام حسین (ع)،

2 گروه فوتونیک دانشکده علوم دانشگاه جامع امام حسین(ع)- تهران - ایران

3 دانشگاه جامع امام حسین (ع)

چکیده

در این مقاله یک حسگر زیستی بلور فوتونی جدید جهت اندازه‌گیری ضریب شکست، پیشنهاد و مورد بررسی قرارگرفته است. سه ساختارِ تک، جفت و سه کاواکی طراحی ومطالعه شدند. در این ساختارها یک کاواک مرکزی به‌عنوان کاواک سنجش بین موج‌برهای ورودی و خروجی ساندویچ شده است. به‌منظور شبیه‌سازی و بررسی نحوه انتشار نور در ساختارها از روش تفاضل محدود در حوزه زمان و بسط موج تخت استفاده ‌شده است. جذب مولکول­های DNA موجود در محلول حسگری (PBS) منجر به تغییر در ضریب شکست مؤثر کاواک‌های سنجش شده و درنتیجه میزان عبوردهی طیفی از موج‌بر تغییر خواهد کرد. با بررسی میزان این تغییرات، فرآیند سنجش و تشخیص میسر می‌شود. با مطالعه اثر پارامترهای مختلف بر طیف خروجی ساختار، به‌منظور دستیابی به بهترین پارامترهای حسگری، مشاهده شد که پارامترهای هندسی ناحیه نقص و همچنین شعاع کاواک‌های کناری کاواک مرکزی، تأثیر قابل ‌ملاحظه‌ای بر طیف ساختارها دارند. نتایج نشان دادند که ساختار تک­کاواکی بیشینه حساسیت برابر باnm/RIU 345 و ساختار سه کاواکی بیشینه فاکتور کیفیت برابر با 531 را دارند. در مقایسه با ساختارهای قبلی انجام‌شده، ساختارهای پیشنهادی در این مقاله به نسبت کارایی به مراتب بهتری از خود نشان می­دهند.

کلیدواژه‌ها

موضوعات


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