Fabrication of a Simulator for Neuron Cell's Action Potential

Abstract

In this paper, neuron cell's action potential and its effective parameters over beating are analyzed. Cell's action potential mechanism can be simulated by fabrication of an equivalent circuit for directed ionic currents using a neuron modeling oscillator. Equivalent circuit consists of capacitor, resistor and transistor. Changing membrane properties such as capacitance and sodium-potassium leakage resistance causes a significant change in action potential. Then, the neuron cell moduling circuit is implemented in microcontroller. The equations should be digitized in order to be sent to microcontroller. Therefore, a discrete algorithm is presented to solve the equations and FHN equations are solved and simulated in discrete form. Then, microcontroller is programmed by the generated hex file of solved equations. In fact, each parameter of the model can be controlled in the fabricated circuit so that it becomes a proper simulator for cellular behavior such as disease and cells malfunction.

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